Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes.

نویسندگان

  • E Nilebäck
  • L Enochson
  • N Altgärde
  • M Schnabelrauch
  • A Lindahl
  • S Svedhem
  • A Kunze
چکیده

The interaction of human-derived chondrocytes and thin hyaluronan layers was studied using the quartz crystal microbalance with dissipation (QCM-D) technique combined with light microscopy. This approach allowed unique real-time monitoring of the interface between the cells and the sensor surface. Our results suggest that the hyaluronan layer is rapidly degraded by chondrocytes.

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عنوان ژورنال:
  • The Analyst

دوره 139 21  شماره 

صفحات  -

تاریخ انتشار 2014